Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart 1 2 3
نویسندگان
چکیده
Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart 1 2 3 Guohua Gong, Xiaoyun Liu, Huiliang Zhang, Shey-Shing Sheu, Wang Wang* 4 5 : Mitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine, University of 6 Washington, Seattle, WA 98109 USA 7 : Center for Translational Medicine, Department of Medicine, Sidney Kimmel Medical College, Thomas 8 Jefferson University, Philadelphia, PA 19107 USA 9 10 Running head: Novel biomarker of mitochondrial respiration 11 12 *: Correspondence address to: Wang Wang, MD, PhD, Mitochondria and Metabolism Center, Department 13 of Anesthesiology and Pain Medicine, University of Washington, 850 Republican Street N121, Seattle, 14 WA 98109 USA. Tel.: (206) 685-4765; Fax: (206) 616-4819; Email: [email protected] 15 16
منابع مشابه
Mitochondrial flash as a novel biomarker of mitochondrial respiration in the heart.
Mitochondrial respiration through electron transport chain (ETC) activity generates ATP and reactive oxygen species in eukaryotic cells. The modulation of mitochondrial respiration in vivo or under physiological conditions remains elusive largely due to the lack of appropriate approach to monitor ETC activity in a real-time manner. Here, we show that ETC-coupled mitochondrial flash is a novel b...
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